Conundrum of Combinatorial Complexity

THE CONUNDRUM OF EUTHANASIA

The Conundrum of Online Prescription Drug Promotion; Comment on “Trouble Spots in Online Direct-to-Consumer Prescription Drug Promotion: A Content Analysis of FDA Warning Letters”

This commentary discusses pertinent issues from Hyosun Kim’s paper on online prescription drug promotion. The study is well-designed and the findings highlight some of the consequences of the Food and Drug Administration’s (FDA’s) decision to deregulate online advertising of prescription drugs. While Kim’s findings confirm some of the early concerns, they also provide a perspective of implement...

An algorithm for multi-objective job shop scheduling problem

Scheduling for job shop is very important in both fields of production management and combinatorial op-timization. However, it is quite difficult to achieve an optimal solution to this problem with traditional opti-mization approaches owing to the high computational complexity. The combination of several optimization criteria induces additional complexity and new problems. In this paper, we pro...

A Simulated Annealing Algorithm for Unsplittable Capacitated Network Design

The Network Design Problem (NDP) is one of the important problems in combinatorial optimization. Among the network design problems, the Multicommodity Capacitated Network Design (MCND) problem has numerous applications in transportation, logistics, telecommunication, and production systems. The MCND problems with splittable flow variables are NP-hard, which means they require exponential time t...

Lateral Nasal Wall Respiratory Epithelial Adenomatoid Hamartoma (REAH): A Diagnostic Conundrum

Introduction: This study aims to report a rare case of a respiratory epithelial adenomatoid hamartoma (REAH) of the lateral nasal wall that had initially presented as a fungating mass, similar to that of a sinonasal malignancy, and its complete removal from the lateral nasal wall.   Case Report: We report the case of a 58-year-old woman who presented to us with a chief complaint of recurrent ri...